Premier League leaders Chelsea visit Bolton Wanderers on Saturday while Manchester United take on Blackburn Rovers and Arsenal face Spurs.
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Australia are next up for England after an unconvincing win over France in their opening Four Nations fixture, with Wigan the venue for the showdown.
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Paul Casey, Lee Westwood, Sergio Garcia and Rory McIlroy are among the big names aiming to win this year's Volvo World Match Play Championship.
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Barnsley, Peterborough and Scunthorpe are the lower league jokers in this week's Carling Cup fourth round pack all looking to take major scalps.
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Liverpool, having lost their last four matches in all competitions, face Premier League leaders Manchester United at Anfield in the game of the weekend.
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Manchester United and Chelsea will put their Premier League title aspirations to the back of their minds this week as they return to European action.
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Anfield hosts a potentially classic Champions League clash between Liverpool and Lyon while defending champions Barcelona face Rubin Kazan.
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Blackburn Rovers and Burnley lock horns on Sunday in an east Lancashire derby which will be as hotly contested as anything in Manchester or on Merseyside.
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Argentina need at least a draw in Uruguay to guarantee their place in the World Cup Finals next summer while Slovenia could also be in South Africa.
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Liam Plunkett, Steve Davies and Adil Rashid have all been included in the England squad for the tour of South Africa but Steve Harmison misses out.
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Republic of Ireland coach Giovanni Trapattoni has the chance to shock his former team when his current side play Italy at Croke Park on Saturday.
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England have already secured their place in the 2010 World Cup but face Ukraine away on Saturday in their penultimate Group Six qualifying match.
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The Presidents Cup line-up in San Francisco ensures that the competition can claim to rival the Ryder Cup in the growing market of team golf.
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Can anybody stop the New York Yankees from running away with the World Series on the back of a stunning regular season in Major League Baseball?
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Title-chasing Manchester City visit an Aston Villa side on Monday that is looking to bounce back after losing to Blackburn Rovers last weekend.
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Jenson Button's quest for the Formula One world title continues in Japan this weekend, with Suzuka the venue for a potentially decisive race.
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Former Manchester United stalwart Steve Bruce takes his Sunderland side to Old Trafford on Saturday evening looking to build on the 5-2 win against Wolves.
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Fulham, Everton and Celtic all return to European action on Thursday during the second round of group-stage matches in the UEFA Europa League.
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