Fulham entertain Sunderland at Craven Cottage and Everton face Tottenham Hotspur at Goodison Park on Sunday as yet another Premier League weekend draws to a close.
With both outfits sitting pretty in the top ten after highly successful starts to the campaign, Roy Hodgson's and Steve Bruce's men will be wanting to further enhance their European credentials with a win this weekend.
Clint Dempsey is in fine goal scoring form for the Cottagers and has struck five in his last six games and they could do with more of the same from their American star.
Strikers Andrew Johnson, Diomansy Kamara and Bobby Zamora are injured and likely to miss out for the hosts and this will leave them thin up top.
Inspirational midfielder Danny Murphy is also likely to remain on the sidelines through injury.
Kenwyne Jones, who could make a return from suspension, has scored in all three of his previous Premier League games against Fulham and will be hoping for more of the same if selected.
The game will be officiated by Mike Dean from the Wirral and both teams should tread carefully before making a challenge in the opposition's penalty area - he has awarded six penalties already this term - more than any other arbiter.
Fulham are online betting favourites to win the clash but Sunderland will be striving to claim just a second away victory away from their Stadium of Light home.
David Moyes' Everton really need a victory but they won't find it easy when they face Harry Redknapp's high-flying Tottenham Hotspur at Goodison Park.
The Toffees have dropped to 16th in the Premier League while this weekend's opponents occupy third place - ahead of rivals Arsenal and Liverpool.
Jermain Defoe will be seeking an improvement of his fantastic return of 11 goals from 12 games so far this term and he is expected to be partnered by Robbie Keane or Peter Crouch.
Moyes will be infuriated that his lengthy injury problems refuse to improve with Mikel Arteta, Phil Jagielka, Victor Anichebe, James Vaughan and Phil Neville suffering from knee injuries.
Youngster Jack Rodwell is nursing a groin strain, Joseph Yobo has injured a hamstring and Leon Osman is out with a foot injury.
History is on the visitors' side ahead of the clash as they have picked up 29 points at Goodison Park - more than any other Premier League outfit.
Spurs, who have hit 33 goals so far, will be buoyed that Everton have kept just one clean sheet in their opening seven home games to date.
The facts favour Spurs but Moyes and his team will be hoping to turn this on its head this weekend.