High-flying Super League teams Warrington Wolves and Wigan Warriors clash at The Halliwell Jones Stadium on Saturday as they look to maintain their 100 per cent records in the opening weeks of the campaign.
With two victories apiece, something has to give this weekend and, to add spice to the fixture, it will be a highly-anticipated derby affair.
Warriors fans make the short trip to Warrington knowing that Australian full-back Cameron Phelps will be missing with an ankle ligament injury.
Warrington prop Garreth Carvell is available after winning his appeal against the one-game ban he had been handed by a disciplinary committee after he was initially found guilty of a forearm offence in last weekend's win against Castleford Tigers.
Leeds Rhinos tackle Salford City Reds at Headingley on Friday night in what is their final game before they face Melbourne Storm in the World Club Challenge on February 28.
The reigning Super League champions have suffered back-to-back defeats in the league and will want to set the record straight with Salford coming to town.
The Reds have lost their first two games of the campaign and look set for another stern test this time around.
Despite Leeds' average start to the new season, they remain overwhelming online sportsbook favourites to win the Super League crown for a fourth successive time.
Hull FC, another team that boasts two wins out of two, will be confident of another success ahead of their meeting with Brian Noble's Crusaders in Wrexham.
Richard Agar's men landed a surprise victory at St Helens before backing that success up with another win against Huddersfield Giants last weekend.
Crusaders recorded a thumping 36-16 win at Salford last Friday and should be growing in confidence after putting their first two points on the board.
Struggling Bradford Bulls will be out to pick up their first win of the campaign with Castleford Tigers ready to lock horns at Grattan Stadium.
The Bulls have succumbed to defeats against Huddersfield and St Helens and sit rock-bottom at this early stage of the campaign.
Last season's Grand Final losers St Helens travel to France on Saturday with a showdown against Catalans Dragons to look forward to.
The Saints' 38-6 drubbing of Bradford last week will put them in good stead ahead of the clash in Perpignan.
Hull KR take on Huddersfield at Craven Park on Sunday with both outfits picking up a win and suffering a defeat in their two games this term.
Nathan Brown's Giants, who lost in the Challenge Cup final to Warrington last August, will be looking for another excellent campaign after finishing third last term.