Castleford Tigers are 37/50 to extend their recent dominance over Leeds Rhinos in Friday night’s Super League clash at Headingley.
The Tigers are Super League's runaway leaders and have enjoyed six straight wins over their big-city neighbours, including their record 66-10 victory in the reverse fixture in March.
Leeds have not beaten Castleford on home soil since 2013 and go into the local derby as 7/6 underdogs on home soil.
Coach Brian McDermott admitted his side are highly motivated for their third meeting of the season, saying: “We're going for Cas. Our blokes are going into battle.
“They're a good team at the top of the tree and six points in front of us. We want the League Leaders' Shield so we're having a crack. We're showing up. If we want the League Leaders', we can't lose.
“Castleford will be disappointed about their Challenge Cup exit but they need to be more worried about us than being out of the cup.”
Leeds are set to be backed by a record crowd for the fixture and McDermott expects the Headingley faithful to be in good voice.
“There's not a better place to be on a Friday night than when there's a big game at Headingley,” he said.
“Our crowd buy into these occasions better than most and really do make it an occasion. We're looking forward to having a big night and a good night.”
Champions Wigan travel to Huddersfield aiming to avoid becoming the first Warriors team since 1903 to go eight league games without a win.
They are 13/25 to end a poor run of form and head coach Shaun Wane is not concerned by recent results, saying: “It doesn't bother me in the slightest.
“We all understand the circumstances we have been in. If that had happened to the team of John Monie, he would have been under the pump. We have got players coming back and we are going to be stronger.”
Huddersfield are 7/4 to take advantage of Wigan’s problems while they are 24/25 with 5.5 points on the handicap.
Wakefield are 31/10 to take Hull's place in the top four when the sides meet at the KCOM Stadium while in Friday's other game, St Helens host second-placed Salford and are 49/100 to inflict a third straight Super League defeat on the Red Devils.